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Papers of the Week

Papers: 2 Jan 2021 - 8 Jan 2021

Human Studies


2020 Dec 26

Dermatol Ther (Heidelb)

Development and Content Validation of Pruritus and Symptoms Assessment for Atopic Dermatitis (PSAAD) in Adolescents and Adults with Moderate-to-Severe AD.


Hall R, Lebwohl MG, Bushmakin AG, L Simpson E, Gooderham MJ, Wollenberg A, Gater A, Wells JR, Cappelleri JC, Hsu M-A, Papacharalambous J, Peeva E, Tallman AM, Zhang W, Chen L
Dermatol Ther (Heidelb). 2020 Dec 26.
PMID: 33382444.


Most patient-reported outcome (PRO) instruments that measure atopic dermatitis (AD) symptoms do not have sufficient documented evidence of content validity to satisfy regulatory agency guidance for inclusion in product-labelling claims in the USA or Europe. The objective of this study was to develop a PRO instrument in accordance with regulatory agency guidance to assess daily AD symptoms during the course of therapy and to establish its content validity and psychometric properties.