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Papers of the Week
Examining the role of transient receptor potential canonical 5 (TRPC5) in osteoarthritis.
Authors
Abstract
Osteo-arthritis (OA) involves joint degradation and usually pain; with mechanisms poorly understood and few treatment options. There is evidence that the transient receptor potential canonical 5 (TRPC5) mRNA expression is reduced in OA patients' synovia. Here we examine the profile of TRPC5 in DRG and involvement in murine models of OA.