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Papers of the Week

Papers: 26 Dec 2020 - 1 Jan 2021

Human Studies, Pharmacology/Drug Development

2020 Dec 28

Br J Clin Pharmacol

Clinical correlates and outcomes associated with pregabalin use among people prescribed opioids for chronic non-cancer pain: A five-year prospective cohort study.


Nielsen S, Gisev N, Leung J, Clare P, Bruno R, Lintzeris N, Larance B, Blyth F, Hall W, Cohen M, Degenhardt L, Farrell M, Campbell G
Br J Clin Pharmacol. 2020 Dec 28.
PMID: 33368473.


Pregabalin has become widely used as an alternative to opioids in treating certain types of chronic non-cancer pain, but few studies have examined its clinical efficacy outside trials. We address this gap by examining the utilization, correlates and clinical outcomes of pregabalin use among an Australian community-based cohort of people prescribed opioids for chronic non-cancer pain.