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Papers of the Week

Papers: 12 Dec 2020 - 18 Dec 2020

Human Studies, Pharmacology/Drug Development


J Pain Res


Efficacy and Safety of ASP0819 in Patients with Fibromyalgia: Results of a Proof-of-Concept, Randomized, Double-Blind, Placebo-Controlled Trial.


Arnold LM, Blauwet M B, Tracy K, Cai N, Walzer M, Blahunka P, Marek GJ
J Pain Res. 2020; 13:3355-3369.
PMID: 33328761.


ASP0819 is a novel, non-opioid K3.1 channel opener that reverses abnormal nerve firing of primary sensory afferent nerves. Currently available treatments for fibromyalgia provide only modest relief and are accompanied by a host of adverse side effects.