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Papers of the Week


Papers: 12 Dec 2020 - 18 Dec 2020


Animal Studies, Pharmacology/Drug Development

PAIN TYPE:
Migraine/Headache


2020 Dec 16


Headache

A non-convulsant delta-opioid receptor agonist, KNT-127, reduces cortical spreading depression and nitroglycerin-induced allodynia.

Authors

Bertels Z, Witkowski WD, Asif S, Siegersma K, van Rijn RM, Pradhan AA
Headache. 2020 Dec 16.
PMID: 33326598.

Abstract

The aim of this study was to determine if the non-convulsant delta-opioid receptor (DOR) agonist, KNT-127, could inhibit migraine-associated endpoints.