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Papers of the Week

Papers: 5 Dec 2020 - 11 Dec 2020

Animal Studies

2020 Nov-Dec

Pain Rep



Neonatal complete Freund’s adjuvant-induced inflammation does not induce or alter hyperalgesic priming or alter adult distributions of C-fibre dorsal horn innervation.


Inflammation during the neonatal period can exacerbate pain severity following reinjury in adulthood. This is driven by alterations in the postnatal development of spinal and supraspinal nociceptive circuitry. However, the contribution of alterations in peripheral nociceptor function remains underexplored.