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Papers of the Week

2020 Nov 25

J Headache Pain



Gray and white matter abnormalities in primary trigeminal neuralgia with and without neurovascular compression.


Wu M, Jiang X, Qiu J, Fu X, Niu C
J Headache Pain. 2020 Nov 25; 21(1):136.
PMID: 33238886.


Previous researches have reported gray and white matter microalterations in primary trigeminal neuralgia (TN) with neurovascular compression (NVC). The central mechanism underlying TN without NVC are unknown but may include changes in specific brain regions or circuitries. This study aimed to investigate abnormalities in the gray matter (GM) and white matter (WM) of the whole brain and the possible pathogenetic mechanism underlying this disease.