I am a
Home I AM A Search Login

Papers of the Week

Papers: 28 Nov 2020 - 4 Dec 2020


Human Studies

2020 Mar 24

J Clin Transl Sci



A non-randomized pilot study to test the feasibility of treating chronic pain and opioid prescription use in rural areas with acceptance and commitment therapy (T-PACT).


Rhyne RL, Rishel Brakey H, Halladay JR, Mottus K, Greiner AK, Salt E, Myers O, Sutton K, Fuentes J, Vowles KE
J Clin Transl Sci. 2020 Mar 24; 4(5):472-476.
PMID: 33244439.


Chronic non-cancer pain (CNCP) involves one-third of the US population, and prescription opioids contribute to the opioid epidemic. The Centers for Disease Control and Prevention emphasizes maximizing non-opioid treatment, but many rural populations cannot access alternative therapies. Clinical and Translational Science Award hubs across four rural states performed a multi-site, single-arm intervention feasibility study testing methods and procedures of implementing a behavioral intervention, acceptance and commitment therapy, in primary care CNCP patients on chronic opioids. Using the CONSORT extension for feasibility studies, we describe lessons learned in recruiting/retaining participants, intervention implementation, data measurement, and multi-site procedures. Results inform a future definitive trial and potentially others conducting rural trials.