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Papers of the Week

Papers: 21 Nov 2020 - 27 Nov 2020

Human Studies, Pharmacology/Drug Development


2020 Oct 05

Pediatr Neurol


Calcitonin Gene-Related Peptide Monoclonal Antibody Use for the Preventive Treatment of Refractory Headache Disorders in Adolescents.


Greene KA, Gentile CP, Szperka CL, Yonker M, Gelfand AA, Grimes B, Irwin SL
Pediatr Neurol. 2020 Oct 05; 114:62-67.
PMID: 33232919.


Monoclonal antibodies to calcitonin gene-related peptide or its receptor have clinical trial evidence in adults with headache, but data are lacking in adolescents. The objective of this study was to describe the safety and efficacy of calcitonin gene-related peptide monoclonal antibody treatment in adolescents with chronic headache disorders.