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Drug Des Devel Ther


Sanguinarine Attenuates Neuropathic Pain by Inhibiting P38 MAPK Activated Neuroinflammation in Rat Model.


Yu C, Li P, Wang Y-X, Zhang K-G, Zheng Z-C, Liang L-S
Drug Des Devel Ther. 2020; 14:4725-4733.
PMID: 33177809.


Neuropathic pain seriously affects life quality, and it is urgent to develop novel drugs with high efficacy and few side effects. Sanguinarine (SG) is a natural plant medicine with anti-inflammatory and neuroprotection effects. This study aimed to investigate the effect of SG on chronic constriction injury (CCI)-induced neuropathic pain.