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Papers of the Week
Gas Chromatographic and Spectrophotometric Determination of Diclofenac Sodium, Ibuprofen, and Mefenamic Acid in Urine and Blood Samples.
Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for the treatment of acute to chronic pain. A simple, fast, and reliable gas chromatographic (GC) method with flame ionization detection has been developed for the determination of NSAIDs such as diclofenac sodium, ibuprofen, and mefenamic acid after derivatization with ethyl chloroformate.