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Papers of the Week

Papers: 7 Nov 2020 - 13 Nov 2020

Human Studies


2020 Nov 09


Prevalence and characteristics of Alice in Wonderland Syndrome in adult migraineurs: Perspectives from a tertiary referral headache unit.


Mastria G, Mancini V, Di Cesare M, Puma M, Alessiani M, Petolicchio B, Viganò A, Di Piero V
Cephalalgia. 2020 Nov 09:333102420968245.
PMID: 33167711.


Migraine affects how the brain processes sensory information at multiple levels. The aberrant integration of visual and somatosensory stimuli is thought to underlie Alice in Wonderland Syndrome, a disorder often reported as being associated with migraine. However, there is still a lack of knowledge about the epidemiology of this syndrome in migraineurs and the association between Alice in Wonderland Syndrome episodes and migraine attacks. Therefore, we conducted a prospective cohort study to systematically evaluate the prevalence and the clinical features of Alice in Wonderland Syndrome in a large sample of patients with migraine.