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Papers of the Week
The protective impact of Trans-Cinnamaldehyde (TCA) against the IL-1β induced inflammation in vitro osteoarthritis model by regulating PI3K/AKT pathways.
Abstract
Osteoarthritis (OA) is a severe joint degeneration disease in elderly people described by the advanced degradation of articular cartilage, which ultimately leads to chronic pain. Trans-cinnamaldehyde (TCA) exerted its anti-inflammatory function in numerous disease syndromes; however, its role in the pathogenesis of OA remains unknown. The current research aimed to explore the potential protective impact of TCA in the progression of osteoarthritis in vitro.