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Papers of the Week

Papers: 24 Oct 2020 - 30 Oct 2020

Human Studies

2020 Oct 21

Clin J Pain

Pain in Youth with Sickle Cell Disease: A Report from the Sickle Cell Clinical Research and Intervention Program.


Alberts NM, Kang G, Li C, Richardson PA, Hodges J, Hankins JS, Klosky JL
Clin J Pain. 2020 Oct 21.
PMID: 33093339.


Pain is prevalent among youth with sickle cell disease (SCD). However, previous research has been limited by small sample sizes, and lacked examinations of developmental differences in pain – which are critical to minimizing the development of chronic pain as youth transition into adulthood. The primary aim of the current study was to compare pain and pain interference across four developmental groups in a large sample of youth with SCD. The secondary aim was to identify risk factors for greater pain and pain interference.