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Papers of the Week

Papers: 3 Oct 2020 - 9 Oct 2020

Human Studies

2020 Jan-Dec

Mol Pain


Preoperative serum circulating microRNAs as potential biomarkers for chronic postoperative pain after total knee replacement.


Giordano R, Petersen K K, Andersen H H, Lichota J, Valeriani M, Simonsen O, Arendt-Nielsen L
Mol Pain. 2020 Jan-Dec; 16:1744806920962925.
PMID: 33021154.


Chronic postoperative pain affects approximately 20% of patients with knee osteoarthritis after total knee replacement. Circulating microRNAs can be found in serum and might act as biomarkers in a variety of diseases. The current study aimed to investigate the preoperative expression of circulating microRNAs as potential predictive biomarkers for the development of chronic postoperative pain in the year following total knee replacement.