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Papers of the Week


2020 Oct 02


Eur J Clin Pharmacol

Benzodiazepine withdrawal in older people: what is the prevalence, what are the signs, and which patients?

Authors

Jobert A, Laforgue E-J, Grall-Bronnec M, Rousselet M, Péré M, Jolliet P, Feuillet F, Victorri-Vigneau C
Eur J Clin Pharmacol. 2020 Oct 02.
PMID: 33006626.

Abstract

Benzodiazepines (BZDs) and related drugs (Z-drugs) are mainly taken chronically, and older people are much more likely to take them on a chronic basis despite recommendations. Withdrawal symptoms could be an obstacle to stopping BZD/Z-drug administration. The main objective of this study is to estimate the prevalence of withdrawal symptoms in patients aged 65 years and older who have experience a stop of BZD/Z-drug. The secondary objectives are to describe the withdrawal symptoms and identify factors associated.