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Papers of the Week

2020 Sep 17

BMC Neurol



Infection-provoked reversible posterior leukoencephalopathy syndrome in an adult with nephrotic syndrome: a case report.


Li K-Y, Chien C-F, Tsai C-L, Chen H-C, Wu M-N, Lai C-L, Liou L-M
BMC Neurol. 2020 Sep 17; 20(1):349.
PMID: 32943018.


Reversible posterior leukoencephalopathy syndrome (RPLS) is a rare and heterogeneous clinico-neuroradiological syndrome characterized by headache, altered mental status, seizures, and visual disturbances. Hypertension and immunosuppression are two of the main factors that predispose an individual to RPLS. However, RPLS can develop when no major risk factors are present. RPLS has been reported in pediatric nephrotic patients, but rarely in adults.