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Papers of the Week

2020 Sep 19

Arch Gynecol Obstet

Endometriosis and irritable bowel syndrome: a systematic review and meta-analysis.


Chiaffarino F, Cipriani S, Ricci E, Mauri P A, Esposito G, Barretta M, Vercellini P, Parazzini F
Arch Gynecol Obstet. 2020 Sep 19.
PMID: 32949284.


Irritable bowel disease and endometriosis are two common diseases characterized by chronic inflammation state and recurrent abdominal pain. As a consequence of sharing of symptoms and chronic inflammation, endometriosis and IBS may coexist and be misdiagnosed and this leads to delays in diagnosis, mismanagement, and unnecessary testing. In recent years, some studies have found higher risk of IBS in women with endometriosis, compared to women without endometriosis. To provide a general overview, we performed a systematic review and a meta-analysis on published data on this issue.