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Papers of the Week

2020 Sep 17

Pain Ther

What to Do and What Not to Do in the Management of Opioid-Induced Constipation: A Choosing Wisely Report.


Alvaro D, Caraceni A T, Coluzzi F, Gianni W, Lugoboni F, Mariangeli F, Massazza G, Pinto C, Varrassi G
Pain Ther. 2020 Sep 17.
PMID: 32940898.


Despite the essential utility of opioids for the clinical management of pain, opioid-induced constipation (OIC) remains an important obstacle in clinical practice. In patients, OIC hinders treatment compliance and has negative effects on quality of life. From a clinician perspective, the diagnosis and management of OIC are hampered by the absence of a clear, universal diagnostic definition across disciplines and a lack of standardization in OIC treatment and assessment.