I am a
Home I AM A Search Login

Papers of the Week

2020 Sep 07

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi



[The correlation between the degree of anxiety/depression and the improvement of subjective and objective symptoms after functional endoscopic sinus surgery in chronic sinusitis].


Feng DD, Huang JJ, Ke X, Liu J, Shen Y, Yang YC
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Sep 07; 55(9):830-836.
PMID: 32911885.


To explore whether the improvement of subjective symptoms and objective grades after endoscopic sinus surgery in patients with chronic sinusitis (CRS) are related to the degree of preoperative anxiety or depression and to provide reference for improving the effects of clinical treatment. The clinical data of one hundred and sixty patients with CRS treated by endoscopic sinus surgery in the First Affiliated Hospital of Chongqing Medical University from April 2018 to August 2019 were collected prospectively. The visual analogue scale (VAS) scores, self-rating anxiety scale (SAS) scores, self-rating depression scale (SDS) scores, Lund-Kennedy scores of nasal endoscopy and the Lund-Mackay scores of CT before and 6 months after surgery were used to analyse the correlation between the scores of anxiety or depression and the subjective and objective scores of patients before and after operation by grouping and layering. One hundred and one males (63.1%) and 59 females (36.9%) with an average age of 47.3 years (18-75 years) were included. Single-sample, independent or paired -test, one-way ANOVA and rank-sum test were used for comparison and correlation analysis was used for the correlation between groups. There was no statistical difference of anxiety or depression between different groups in terms of age, gender and course in the 160 effective patients ( values were -0.151, -0.487, -0.846, all values>0.05; values were -0.473, -1.302, -1.069, all values>0.05). And the degree of preoperative anxiety or depression was positively correlated with the subjective scores, including overall discomfort, nasal obstruction, runny nose and olfactory decline ( values were 0.515, 0.606, 0.424, 0.306, all values<0.01; values were: 0.518, 0.584, 0.448, 0.308, all values<0.01), but not significantly correlated with objective scores of Lund-Mackay and Lund-Kennedy (all value0.05). Moreover, as far as the symptoms of overall discomfort, nasal obstruction, headache and runny nose, the results of one-way ANOVA showed that the improvement of symptoms in patients with serious anxiety or depression was worse than that of the normal, mild and moderate patients (all values<0.05). However, there was no significant difference in the scores of Lund-Kennedy 6 months after surgery between them (both values>0.05). The state of anxiety or depression affects the improvement of symptoms after endoscopic sinus surgery for CRS patients. Compared with the patients with normal and mild to moderate anxiety or depression, the improvement of symptoms in patients with severe anxiety and depression is worse. It is necessary to evaluate the anxiety or depression of the patients with CRS who are going to undergo endoscopic sinus surgery.