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Papers of the Week

Papers: 5 Sep 2020 - 11 Sep 2020

Human Studies, Pharmacology/Drug Development

2020 Sep 04


Dissociative and Analgesic Properties of Ketamine Are Independent.


Gitlin J, Chamadia S, Locascio JJ, Ethridge BR, Pedemonte JC, Hahm EY, Ibala R, Mekonnen J, Colon KM, Qu J, Akeju O
Anesthesiology. 2020 Sep 04.
PMID: 32898213.


Ketamine is a dissociative anesthetic with analgesic properties. Ketamine's analgesic properties have been suggested to result from its dissociative properties. To the authors' knowledge, this postulate is unsubstantiated. The authors hypothesize that the dissociative and analgesic properties of ketamine are independent.