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Papers of the Week

2020 Sep 02

Exp Biol Med (Maywood)

Acupuncture reduces pain in rats with osteoarthritis by inhibiting MCP2/CCR2 signaling pathway.


Li B, Jing L, Jia L, Qian T, Jianyi C, Zhongsheng H, Xiaohong Z, Guowei C
Exp Biol Med (Maywood). 2020 Sep 02:1535370220952342.
PMID: 32878462.


Osteoarthritis (OA) is the most common form of arthritis, affecting an estimated 302 million people worldwide, but the mechanism of OA is far away understood. Acupuncture has been widely used in treating with chronic pain, but how does acupuncture work is still unclear. In this essay, we investigated the molecular target of acupuncture and found new mechanism of the pathogenesis in knee OA. Our results could provide new analgesic mechanisms and find new targets for acupuncture analgesia in OA. In a word, the study can help further understanding and provides more evidence of the clinical use of acupuncture in treating OA.