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Papers of the Week

2020 Sep-Oct

J Clin Orthop Trauma



Modic changes – An evidence-based, narrative review on its patho-physiology, clinical significance and role in chronic low back pain.


Viswanathan V K, Shetty A P, Rajasekaran S
J Clin Orthop Trauma. 2020 Sep-Oct; 11(5):761-769.
PMID: 32879563.


Lumbar degenerative spinal ailments are the most important causes for chronic low back pain. Modic changes (MC) are vertebral bone marrow signal intensity changes seen on MRI, commonly in association with degenerative disc disease (DDD). Despite being widely studied, majority of issues concerning MC are still controversial. The current narrative, evidence-based review comprehensively discusses the various aspects related to MC.