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Papers of the Week

2020 Aug 26

BMC Anesthesiol



Sufentanil postoperative analgesia reduce the increase of T helper 17 (Th17) cells and FoxP3 regulatory T (Treg) cells in rat hepatocellular carcinoma surgical model: A randomised animal study.


Peng Y, Yang J, Guo D, Zheng C, Sun H, Zhang Q, Zou S, Zhang Y P, Luo K, Candiotti KA
BMC Anesthesiol. 2020 Aug 26; 20(1):212.
PMID: 32847505.


Surgery-related pain and opioids might exacerbate immune defenses in immunocompromised cancer patients which might affect postoperativd overall survival. Sufentanil is a good postoperative pain control drug,the present study aimed to figure out whether it effect T cell immunity in rat hepatocellular carcinoma surgical model.