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Papers of the Week

2020 Aug 10

J Mycol Med

Diagnosis at different stages of paracoccidioidomycosis with oral manifestation: Report of two cases.


de Oliveira MS, Fernandes TB, de Lima Medeiros Y, de Abreu Guimarães LD, Sanches GT, de Carvalho MF, Vilela EM
J Mycol Med. 2020 Aug 10:101025.
PMID: 32855057.


Paracocciodiomycosis (PCDM) is a chronic systemic fungal infection, mainly affecting residents and rural workers, being characterized by a long incubation period, which it can take months or years without clinical manifestations, making diagnosis late and difficult. Depending on the stage of the disease, it can cause sequelae and low quality of life, so its correct diagnosis is of great importance for the accurate treatment. Therefore, the aim of this report is to present two cases of diagnosis of patients with PCDM at different stages, who developed chronic manifestations, pain, clinical involvement of the oral cavity and in one case also presented lung injury with fibrosis, as well as to weight loss, dysphagia and cachexia. Both of patients were treated with antifungal therapy and it was observed total remission of the lesions and no recurrences were detected.