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Papers of the Week

Papers: 22 Aug 2020 - 28 Aug 2020

Animal Studies


J Pain Res


Spinal N-Cadherin/CREB Signaling Contributes to Chronic Alcohol Consumption-Enhanced Postsurgical Pain.


Ma Y, Zhang X, Li C, Liu S, Xing Y, Tao F
J Pain Res. 2020; 13:2065-2072.
PMID: 32848450.


It has been reported that N-cadherin and cAMP response element binding protein (CREB) in the spinal cord are critical for synaptogenesis and regulation of excitatory synapse function, which could underlie chronic pain development. The aim of the present study was to investigate the role of spinal N-cadherin/CREB signaling in postsurgical pain chronicity following chronic alcohol consumption.