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Papers of the Week

Papers: 22 Aug 2020 - 28 Aug 2020

Animal Studies, Pharmacology/Drug Development

2020 Aug 27

Eur J Pain

N-Docosahexaenoyl ethanolamine (Synaptamide) has antinociceptive effects in male mice.


Frances Paton K, Shirazi R, Vyssotski M, Maree Kivell B
Eur J Pain. 2020 Aug 27.
PMID: 32852071.


N-docosahexaenoyl ethanolamine (DHEA; also known as synaptamide) binds to both the CB1 and CB2 cannabinoid receptors and has anti-inflammatory properties in vitro. However, the in vivo effects of DHEA are unknown. Therefore, this study was designed to understand the effects of DHEA in models of pain and inflammation in mice.