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Papers of the Week

Papers: 22 Aug 2020 - 28 Aug 2020

Animal Studies

2020 Aug 21

Physiol Behav

Skin temperature contribution to the decrease in withdrawal latency following chronic constriction injury.


Voderova L, Sandera S, Drobil T, Plevova B, Vaculin S
Physiol Behav. 2020 Aug 21:113147.
PMID: 32835779.


Chronic constriction injury (CCI) is widely used as an animal neuropathic pain model. Neuropathic pain is considered to exist when withdrawal latency to thermal stimulation is decreased after inducing a CCI to the sciatic nerve. However, it is known that CCI leads to changes in skin temperature and that skin temperature can affect withdrawal latency. Aim of this study was to compare withdrawal latencies of constricted and contralateral hind limbs, to thermal stimulation, at the same artificially-induced skin temperatures.