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Papers of the Week

Papers: 22 Aug 2020 - 28 Aug 2020

2020 Aug 22

Ann Neurol

DBS for chronic cluster headache: meta-analysis of individual patient data.


Nowacki A, Schober M, Nader L, Saryyeva A, Nguyen KTA, Green AL, Pollo C, Krauss JK, Fontaine D, Aziz TZ
Ann Neurol. 2020 Aug 22.
PMID: 32827225.


Deep brain stimulation (DBS) is a treatment alternative for refractory chronic Cluster headache (CCH). Despite several recent prospective case series reporting on good outcome, the effectiveness and the optimal stimulation target of DBS for CCH remain unclear. We aimed to obtain precise estimates and predictors of long-term pain relief in an individual patient data meta-analysis. Further, we aimed to construct a probabilistic stimulation map of effective DBS.