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Papers of the Week


2020 Aug 19


Infect Disord Drug Targets

Determining serum levels of IL-10 and IL-17 in patients with low back pain caused by lumbar disc degeneration.

Authors

Banimostafavi E S, Fakhar M, Abediankenari S, Alizadeh-Navaei R, Mehdipour K, Omrani-Nava V, Majidi H
Infect Disord Drug Targets. 2020 Aug 19.
PMID: 32819250.

Abstract

Low Back pain (LBP) is a common health problem that affects different aspects of a person's life. Degeneration of the intervertebral disc is a major cause of LBP. Interleukin-17 (IL-17) is a pro-inflammatory cytokine. In contrast, interleukin-10 (IL-10) prevents the occurrence of immune over-stimulation by inhibiting inflammation. The purpose of this study was to evaluate the serum levels of these cytokines in LBP patients and in the control group.