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Papers of the Week


2020 Aug 21


JAMA

Effect of Remdesivir vs Standard Care on Clinical Status at 11 Days in Patients With Moderate COVID-19: A Randomized Clinical Trial.

Authors

Spinner CD, Gottlieb RL, Criner GJ, Arribas López J R, Cattelan A M, Soriano Viladomiu A, Ogbuagu O, Malhotra P, Mullane KM, Castagna A, Chai L Y A, Roestenberg M, Tsang O T Y, Bernasconi E, Le Turnier P, Chang S-C, SenGupta D, Hyland RH, Osinusi AO, Cao H, et al.
JAMA. 2020 Aug 21.
PMID: 32821939.

Abstract

Remdesivir demonstrated clinical benefit in a placebo-controlled trial in patients with severe coronavirus disease 2019 (COVID-19), but its effect in patients with moderate disease is unknown.