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Papers of the Week

Papers: 15 Aug 2020 - 21 Aug 2020

Pharmacology/Drug Development


2020 Aug 19

Expert Opin Drug Saf

CGRP inhibitors for migraine prophylaxis: a safety review.


Rivera-Mancilla E, Villalón CM, Maassen Van Den Brink A
Expert Opin Drug Saf. 2020 Aug 19.
PMID: 32811190.


Since calcitonin gene-related peptide (CGRP) plays an important role in the pathophysiology of migraine via the activation of the trigeminovascular system, the newest prophylactic treatments directly block CGRP or its receptor. However, the safety of these novel antimigraine drugs is not yet sufficiently established.