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Papers of the Week

Home / Publications / Pain Research Forum / Papers of the Week / Circular RNA ITCH Suppresses Cell Proliferation but Induces Apoptosis in Oral Squamous Cell Carcinoma by Regulating miR-421/PDCD4 Axis.

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2020


Cancer Manag Res


http://www.ncbi.nlm.nih.gov/pubmed/32765068?dopt=Abstract


12

Circular RNA ITCH Suppresses Cell Proliferation but Induces Apoptosis in Oral Squamous Cell Carcinoma by Regulating miR-421/PDCD4 Axis.

Authors

Circular RNA ITCH Suppresses Cell Proliferation but Induces Apoptosis in Oral Squamous Cell Carcinoma by Regulating miR-421/PDCD4 Axis.
Hao C, Wangzhou K, Liang Z, Liu C, Wang L, Gong L, Tan Y, Li C, Lai Z, Hu G
Cancer Manag Res. 2020; 12:5651-5658.
PMID: 32765068.

Abstract

Circular RNAs (circRNAs), a group of covalently closed non-coding RNAs, serve critical regulatory roles in many human cancers, including oral squamous cell carcinoma (OSCC). The purpose of this study was to investigate the functional role of circular RNA ITCH (circ-ITCH) in OSCC and the underlying mechanisms.
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