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Papers of the Week

2020 Jul-Aug

Pain Rep



Genomic analysis of 21 patients with corneal neuralgia after refractive surgery.


Yuan J-H, Schulman BR, Effraim PR, Sulayman D-H, Jacobs DS, Waxman SG
Pain Rep. 2020 Jul-Aug; 5(4):e826.
PMID: 32766464.


Refractive surgery, specifically laser-assisted in situ keratomileusis and photorefractive keratectomy, are widely applied procedures to treat myopia, hyperopia, and astigmatism. After surgery, a subgroup of cases suffers from persistent and intractable pain of obscure etiology, thought to be neuropathic. We aimed to investigate the contribution of genomic factors in the pathogenesis of these patients with corneal neuralgia.