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Papers of the Week

Papers: 18 Jul 2020 - 24 Jul 2020

Pharmacology/Drug Development

2020 Jul 18

Expert Opin Ther Pat

Transient receptor potential ankyrin 1 (TRPA1) antagonists: a patent review (2015-2019).



TRPA1 is a non-selective cation channel predominantly expressed in sensory neurons, and functions as an irritant sensor for a plethora of noxious external stimuli and endogenous ligands associated with cell damage. Due to its involvement in pain, itch, and respiratory syndromes, TRPA1 has been pursued as a promising drug target.