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Papers of the Week

Papers: 11 Jul 2020 - 17 Jul 2020

Human Studies

2020 Jul 14

JMIR Res Protoc

Study protocol for Long-Term Opioid Therapy in Spine Center Outpatients: The Spinal Pain Opioid Cohort (SPOC).


Manniche C, Stokholm L, Ravn SL, Andersen TE, Brandt LPA, Rubin KH, Schiøttz-Christensen B, Andersen LL, Skousgaard SG
JMIR Res Protoc. 2020 Jul 14.
PMID: 32663155.


Spinal pain is the leading worldwide cause of patient-years lived with chronic pain and disability. While opioids are well documented as an effective short-term pain-relieving medication, more than a few weeks of treatment may result in a diminishing clinical effect as well as the development of addictive behavior. Even though opioid addiction in pain patients is a major problem commonly experienced in the clinic, no reference material exists on the scope of long-term problems in novel opioid users and the link to clinical outcomes.