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Papers of the Week
Do Early Non-Steroidal Anti-Inflammatory Drugs for Analgesia Worsen Acute Kidney Injury in Critically Ill Trauma Patients? An Inverse Probability of Treatment Weighted Analysis.
Abstract
Administration of NSAIDs for acute post-traumatic analgesia is increasing in popularity as an alternative to opioids despite reservations regarding its potential impact on the development of acute kidney injury (AKI). We hypothesized that early NSAID administration for analgesia would be associated with worsened renal function in severely injured trauma patients.