I am a
Home I AM A Search Login

Papers of the Week

Papers: 27 Jun 2020 - 3 Jul 2020

2020 Jun 25

Arthritis Care Res (Hoboken)

Is There Any Role for Opioids in the Management of Knee and Hip Osteoarthritis? A Systematic Review and Meta-Analysis.


Osani MC, Lohmander SL, Bannuru RR
Arthritis Care Res (Hoboken). 2020 Jun 25.
PMID: 32583972.


Opioids have long been prescribed for chronic pain conditions, including osteoarthritis (OA). However, there is little information about their temporal efficacy or differences in efficacy and safety between opioids with strong versus weak/intermediate μ opioid receptor binding affinity. To explore these research questions, we conducted a systematic review and meta-analyses of randomized controlled trials (RCTs) conducted in patients with knee and/or hip OA.