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Papers of the Week

2020 Jun 17


Behavioral Survey of Effects of Pulsed Radiofrequency on Neuropathic and Nociceptive Pain in Rats: Treatment Profile and Device Implantation.


Huang R-Y, Poree L, Ho K-Y, Tsai S-Y, Liu Y-C, Tan P-H, Wen Y-R
Neuromodulation. 2020 Jun 17.
PMID: 32558126.


Pulsed radiofrequency (PRF) stimulation is widely used for intractable pain; however, there is no consensus on treatment protocols and appropriate types of pain. We compared effectiveness of bipolar and unipolar PRF on neuropathic or inflammatory pains, and of targets at the dorsal root ganglion (DRG) and sciatic nerve (SN). We also examined efficacy of repetitive PRF stimulations. This preclinical study could serve as an extensive survey before human trials.