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Ther Adv Chronic Dis


The numbers of peripheral regulatory T cells are reduced in patients with psoriatic arthritis and are restored by low-dose interleukin-2.


Wang J, Zhang S-X, Hao Y-F, Qiu M-T, Luo J, Li Y-Y, Gao C, Li X-F
Ther Adv Chronic Dis. 2020; 11:2040622320916014.
PMID: 32523664.


Although regulatory T cells (Tregs) play crucial roles in the maintenance of immune hemostasis, the numbers of peripheral Tregs in patients with psoriatic arthritis (PsA) remain unclear. We measured these numbers and the efficacy and safety of low-dose interleukin-2 (IL-2) therapy.