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Papers of the Week

Papers: 6 Jun 2020 - 12 Jun 2020

Animal Studies

2020 Jun 09

J Neuroinflammation



High-salt diet decreases mechanical thresholds in mice that is mediated by a CCR2-dependent mechanism.


Fan A, Oladiran O, Shi X Q, Zhang J
J Neuroinflammation. 2020 Jun 09; 17(1):179.
PMID: 32517772.


Though it is well-known that a high-salt diet (HSD) is associated with many chronic diseases, the effects of long-term high-salt intake on physiological functions and homeostasis remain elusive. In this study, we investigated whether and how an HSD affects mouse nociceptive thresholds, and myeloid cell trafficking and activation.