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Papers of the Week
High-salt diet decreases mechanical thresholds in mice that is mediated by a CCR2-dependent mechanism.
Abstract
Though it is well-known that a high-salt diet (HSD) is associated with many chronic diseases, the effects of long-term high-salt intake on physiological functions and homeostasis remain elusive. In this study, we investigated whether and how an HSD affects mouse nociceptive thresholds, and myeloid cell trafficking and activation.