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Papers of the Week

2020 Jun 02

J Ethnopharmacol

An integrated strategy for discovering effective components of Shaoyao Gancao decoction for treating neuropathic pain by the combination of partial least-squares regression and multi-index comprehensive method.


Feng L-M, Chen Y-Y, Xu D-Q, Fu R-J, Yue S-J, Zhao Q, Huang Y-X, Bai X, Wang M, Xing L-M, Tang Y-P, Duan J-A
J Ethnopharmacol. 2020 Jun 02:113050.
PMID: 32502651.


Neuropathic pain, the incidence of which ranges from 5 to 8% in the general population, remains challenge in the treatment. Shaoyao Gancao decoction (SGD) is a Chinese classical formula used to relieve pain for thousands of years and has been applied for neuropathic pain nowadays. However, the effective components of SGD for the treatment of neuropathic pain remains unclear.