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Papers of the Week

Papers: 30 May 2020 - 5 Jun 2020


2020 Jun 01

Ann Allergy Asthma Immunol

New and Emerging Treatments for Inflammatory Itch.


Erickson S, Heul A V, Kim BS
Ann Allergy Asthma Immunol. 2020 Jun 01.
PMID: 32497711.


Chronic pruritus, or itch lasting >6 weeks, is a common symptom and has a profoundly negative impact on quality of life. While many primary dermatologic disorders such as atopic dermatitis and chronic urticaria are characterized by pruritus, numerous other allergic, hepatobiliary, lymphoproliferative, neurologic, and renal disorders are associated with chronic pruritus. Itch involves complex interactions orchestrated by a variety of factors released from and acting on the skin, immune system, and the sensory nervous system. This review summarizes recent therapeutic developments for chronic pruritus with a focus on allergic and type 2 inflammatory pathways.