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Papers of the Week

Papers: 30 May 2020 - 5 Jun 2020

Human Studies

2020 May 29

Pain Pract

A Regions of Interest Voxel-based morphometry study of the human brain during high-frequency spinal cord stimulation in patients with Failed Back Surgery Syndrome.


De Groote S, Goudman L, Linderoth B, Buyck F, Rigoard P, De Jaeger M, Van Schuerbeek P, Peeters R, Sunaert S, Moens M
Pain Pract. 2020 May 29.
PMID: 32470180.


The effectiveness of Spinal Cord Stimulation (SCS) as pain-relieving treatment for Failed Back Surgery Syndrome (FBSS) has already been demonstrated. However, potential structural and functional brain alterations resulting from subsensory SCS are less clear. The aim of this study is to test structural volumetric changes in a priori chosen regions of interest related to chronic pain after 1 month and 3 months of high-frequency SCS, in patients with FBSS.