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Papers of the Week

2020 Mar 01

J Appl Lab Med



Development and Validation of a Free Carbamazepine Assay on an Automated Chemistry Analyzer.


Zhang X, Boyert N, Mitro M, Tang X, Bowers K, McShane AJ
J Appl Lab Med. 2020 Mar 01; 5(2):357-362.
PMID: 32445379.


Carbamazepine is an effective drug for treating seizures and trigeminal neuralgia. Therapeutic drug monitoring of free carbamazepine in serum can be useful in situations that drug–protein binding is altered to guide regimen adjustment and to aid in the diagnosis of clinical toxicity.