I am a
Home I AM A Search Login

Papers of the Week

2020 May 20

Expert Rev Neurother

Targeting CGRP for migraine treatment: mechanisms, antibodies, small molecules, perspectives.


De Matteis E, Guglielmetti M, Ornello R, Spuntarelli V, Martelletti P, Sacco S
Expert Rev Neurother. 2020 May 20.
PMID: 32434430.


Calcitonin Gene-Related Peptide (CGRP) has gradually emerged as a suitable therapeutic target to treat migraine. Considering the social and economic burden of migraine, it is fundamental to optimize the disease management with efficacious and safe treatments. In this scenario, drugs targeting GCRP, monoclonal antibodies (MoAbs) and gepants, represent new therapeutic strategies.