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Papers of the Week

2020 May 17

Neurophysiol Clin

Is the analgesic effect of motor cortex stimulation somatotopically driven or not?


Pommier B, Quesada C, Nuti C, Peyron R, Vassal F
Neurophysiol Clin. 2020 May 17.
PMID: 32434693.


Mechanisms of analgesic efficacy related to motor cortex stimulation (MCS) remain poorly understood. Specifically, it is unclear whether pain relief is somatotopically driven or not. We present three illustrative case-reports of MCS in which unintentional stimulation setting errors occurred, leading to differential (and reversible) pain relief outcomes across the hemi-body.