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Papers of the Week

Papers: 16 May 2020 - 22 May 2020

Human Studies, Pharmacology/Drug Development


2020 May 18

Eur J Neurol

Evaluation of the concomitant use of oral preventive treatments and OnabotulinumtoxinA in chronic migraine: the PREVENBOX study.


Alpuente A, Gallardo V J, Torres-Ferrús M, Santos-Lasaosa S, Guerrero Á, Laínez J M, Viguera J, Gago-Veiga A, Irimia P, Del Río M S, Pozo-Rosich P
Eur J Neurol. 2020 May 18.
PMID: 32421912.


OnabotulinumtoxinA is an effective preventive treatment for chronic migraine. In chronic migraine, besides a reduction in headache frequency, a decreased reliance on oral prophylactics is also indicative of treatment effectiveness. This study aimed to quantify the change in the use of oral prophylactics after treatment with onabotulinumtoxinA in patients with chronic migraine.