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Papers of the Week

Papers: 9 May 2020 - 15 May 2020


Human Studies

2020 May 10

Pain Med

Evidence of Neural Microstructure Abnormalities in Type I Chiari Malformation: Associations Among Fiber Tract Integrity, Pain, and Cognitive Dysfunction.


Houston JR, Hughes ML, Bennett IJ, Allen PA, Rogers JM, Lien M-C, Stoltz H, Sakaie K, Loth F, Maleki J, Vorster SJ, Luciano MG
Pain Med. 2020 May 10.
PMID: 32388548.


Previous case-control investigations of type I Chiari malformation (CMI) have reported cognitive deficits and microstructural white matter abnormalities, as measured by diffusion tensor imaging (DTI). CMI is also typically associated with pain, including occipital headache, but the relationship between pain symptoms and microstructure is not known.