I am a
Home I AM A Search Login

Papers of the Week

Papers: 2 May 2020 - 8 May 2020

Human Studies

2020 Jan-Dec

Mol Pain


Chronic Postoperative Pain After Hysterectomy for Endometrial Cancer: A Metabolic Profiling Study.


Lunde S, Nguyen H T, Petersen KK, Arendt-Nielsen L, Krarup HB, Søgaard-Andersen E
Mol Pain. 2020 Jan-Dec; 16:1744806920923885.
PMID: 32375547.


One out of seven women will develop a state of chronic postoperative pain following robot-assisted hysterectomy for endometrial cancer. Recently, metabolic studies have indicated that circulating lipids and lipoproteins could act as nociceptive modulators and thereby influence the induction and perpetuation of pain. The objectives of this explorative study were (1) to examine the preoperative serologic variations in concentrations of lipids, lipoproteins, and various low-molecular metabolites in patients with and without chronic postoperative pain after robot-assisted hysterectomy and (2) to explore if any of these serological biomarkers were predictive for development of chronic postoperative pain.